RE: Cholodin supplement
On the subject of medications and supplements(and I dont mean to side tract this thread) but I was reading a few articles last week about Coconut oil both topically and ingested. It seems to be the latest and greatest thing since High Buckle shoes! :) They even claim that it helps with energy levels, dementia, digestion and many more benefits. Anyone have any first hand info? Im giving the "girls" one teaspoon a day with their meal...only for about three days now so havent noticed anything yet.
New England Journal of Medicine. There have been studies on coconut oil and the results have been amazing.
RE: Cholodin supplement
You might want to review this
Applies to clonidine: oral suspension extended release, oral tablet, oral tablet extended release
Other dosage forms:
transdermal film extended release
Get emergency medical help if you have any of these signs of an allergic reaction while taking clonidine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
fast or pounding heartbeats, tremors;
a very slow heart rate (fewer than 60 beats per minute);
feeling short of breath, even with mild exertion;
swelling, rapid weight gain;
confusion, hallucinations;
flu symptoms;
urination problems; or
feeling like you might pass out.
Other common side effects may include:
drowsiness, dizziness;
feeling tired or irritable;
cold symptoms such as runny or stuffy nose, sneezing, cough, sore throat;
mood changes;
sleep problems (insomnia), nightmares;
headache, ear pain;
mild fever;
feeling hot;
constipation, diarrhea, pain in your upper stomach;
dry mouth, increased thirst; or
loss of interest in sex, impotence, difficulty having an orgasm.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For Healthcare Professionals
Applies to clonidine: compounding powder, injectable solution, oral suspension extended release, oral tablet, oral tablet extended release, transdermal film extended release
Other
The most common adverse side effects are related to the alpha-adrenergic blocking effects of clonidine. These side effects are dose-related, typically decrease over time, and mostly affect the nervous system, cardiovascular system, and the gastrointestinal system.
Nervous system
Nervous system side effects have included drowsiness (28%), dizziness (9%), somnolence (19%), fatigue (13%), headache (19%), irritability (6%), insomnia (6%), nightmares (3%), body temperature increased (1%), abnormal sleep-related event (1%), and tremor (3%). Patients with decreased autoregulation of cerebral blood flow appear to be at increased risk for clonidine-induced cerebral hypoperfusion if blood pressure is lowered too much or too quickly. This may be important in some elderly patients. Confusion (13.2%) and hallucinations (5.3%) have been reported with epidural usage. Dose-dependent sedative effects, memory impairment, and reduced cognitive performance have been reported in subjects receiving intravenous clonidine.
A study of 13 patients who had pre- and post-clonidine cerebral blood flow (CBF) measured by nuclear scanning revealed that patients with an initially high pretreatment CBF tended to demonstrate decreased CBF after clonidine therapy.
Patients with traumatic spinal cord injury receiving clonidine may experience a delayed-onset of sedation regardless of the route of administration (i.e., intrathecal, intramuscular).
Cardiovascular
Cardiovascular side effects have included hypotension and sinus and atrioventricular arrhythmias. Postural hypotension occurs in 2% of patients. Rebound hypertension (which may be worse than pretreatment values) can present as irritability, tremors, headache, increased salivation, and palpitations. Rebound hypertension may be minimized by gradual reduction of dosage over two to four days.
Hypotension with epidural clonidine has been reported in 45% of 38 patients in one study. Hypotension occurred more commonly in the first four days, in women, in lower weight patients, and those receiving higher dosages.
Other cardiovascular side effects have included sinus bradycardia in approximately 0.3% of patients. A rare case of sinus arrest associated with clonidine has been reported. Patients with preexisting sinus node dysfunction, patients who have developed bradycardia while taking other sympatholytic agents, patients who are on another sympatholytic agent, and patients with renal dysfunction are at increased risk of clonidine-associated sinus bradycardia. Clonidine may cause hypertension in some patients with idiopathic orthostatic hypotension, particularly those with autonomic nervous system dysfunction. There have also been reports of congestive heart failure, electrocardiographic abnormalities (i.e., sinus node arrest, junctional bradycardia, high degree AV block, and arrhythmias), palpitations, Raynaud's phenomenon, syncope, and tachycardia. Cases of sinus bradycardia and atrioventricular block have been reported, both with and without the use of concomitant digitalis.
A case of sinus arrest associated with clonidine has been reported. A 65-year-old man with diabetes, hypertension and unexplained syncope developed more frequent syncope and dizziness associated with documented episodes of sinus arrest during the first week of clonidine therapy. The patient had no hypoglycemia or orthostatic changes. The syncope and dizziness resolved upon discontinuation of clonidine; continuous electrocardiographic monitoring revealed a gradual and complete disappearance of sinus pauses. Junctional bradycardia and AV heart block have also been reported.
Ventricular tachycardia (VT) relatively refractory to lidocaine, but responsive to intravenous phentolamine, has been associated with clonidine withdrawal (case report). The authors believe that the VT was probably produced by humoral or neural stimulation of unregulated myocardial alpha-adrenergic receptors.
Transdermal clonidine has been implicated with hypertension in a quadriplegic patient with a C4 spinal lesion. The proposed mechanism is predominance of clonidine's peripheral alpha-1 adrenergic effects due to the patient's autonomic dysfunction, resulting in vasoconstriction and hypertension.
Sinus bradycardia or other supraventricular bradyarrhythmias are more likely in patients with underlying renal dysfunction.
In one case report, severe hypotension occurred during separation from cardiopulmonary bypass in a patient given intrathecal clonidine. The patient responded to volume expansion and use of vasoconstrictors.
Gastrointestinal
Gastrointestinal side effects have most commonly included dry mouth (30%) and constipation (15%), abdominal pain, anorexia, nausea, vomiting, diarrhea (1%), parotitis, pseudo-obstruction (including colonic pseudo-obstruction), and salivary gland pain. Nausea (13.2%) and vomiting (10.5%) have been reported with epidural clonidine.
Genitourinary
Genitourinary side effects have included impotence in male patients (24%), retrograde and delayed ejaculation, and an inability to achieve orgasm in female patients.
Dermatologic
A 66-year-old woman with a history of psoriasis in remission developed erythematous, scaly plaques on the extensor surfaces of her forearms within three days after beginning clonidine therapy for control of flushing. The author of this case report suspected that clonidine may cause a fall in intracellular cAMP, leading to epidermal cell proliferation, and, in some cases, a psoriasiform eruption.
Dermatologic reactions have been reported in 10% to 38% of patients who use transdermal clonidine. These reactions include psoriasis exacerbations, local dermatitis and/or pigmentation, alopecia, angioneurotic edema, hives, pruritus, rash, and urticaria.
Psychiatric
Psychiatric side effects have included emotional disorder (5%), aggression (1%), tearfulness (3%) and rare reports of depression, which has been the most common psychiatric reaction to clonidine. Rare cases of frank psychoses and delirium have been associated with clonidine withdrawal. Hallucinations have been reported postmarketing.
Endocrine
Endocrinologic side effects have been limited to rare cases of gynecomastia, hyperprolactinemia, or hyperglycemia.
A 68-year-old black man with hypertension, status post unilateral nephrectomy, was incidentally found to have 4+ proteinuria, 1+ glycosuria, new elevated blood glucose levels, and between 1.8 and 5.4 grams of protein per 24-hour urine collection within 6 weeks after starting clonidine. The signs and symptoms of diabetes and the nephrotic syndrome disappeared within five months after discontinuation of clonidine. Because of his solitary kidney, a renal biopsy was not performed.
Musculoskeletal
Musculoskeletal side effects have included leg cramps and muscle or joint pain. Moderately severe myalgia has been associated with the use of clonidine in patients treated for opioid withdrawal symptoms.
Immunologic
Immunologic side effects have rarely been reported and include one case of immune-complex disease.
A 46-year-old woman developed forearm edema, mild thenar atrophy, and skin hypopigmentation within three months after beginning clonidine for perimenopausal flushing. Electromyelography was consistent with carpal tunnel syndrome. At surgical decompression, a skin biopsy revealed changes consistent with immune-complex disease. The patient's signs and symptoms abated after physical therapy and discontinuation of clonidine.
Respiratory
A 9-year-old boy with asthma developed a severe asthma attack after an oral clonidine stimulation test. He required hospitalization. The authors of this case report suspect that clonidine may have caused acute pulmonary artery vasoconstriction (directly), which could have decreased pulmonary blood flow, producing relative pulmonary hypoxemia, setting off an asthma attack.
Respiratory system reactions have included nasal congestion (5%), asthma (1%), and nasopharyngitis (3%). A case of severe bronchospasm associated with clonidine has been reported in the pediatric literature.
Ocular
Ocular side effects have included accommodation disorder, blurred vision, burning of the eyes, decreased lacrimation, and dryness of the eyes.
Metabolic
Metabolic side effects have included thirst (3%) and throat pain (6%).
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Read more at http://www.drugs.com/sfx/clonidine-side-effects.html#9Bfxiob5v3vouiPs.99
RE: toilet
Sometimes stuff gets stuck down there. Reach your arm down the hole as far as you can. When down to the max feel around for anything chunky. Grab it and squeeze it between your fingers until it gets smaller then dump some water in it (After you pull your arm out of coarse}. Do this once a month for regular maintenance. Wash your hands before cooking. I do have a self help video available. Hope this helps
RE: Bought new tires today, gone are the Michelins!
Good riddance on the Michelins, imo. I agree with op. Hope the Generals work out for you. Think I'm pretty much a BFG guy now.
Do some research and you would be shocked by who makes BF Goodrich
RE: Hot water heater
If you have hot water why do you need a heater?
My water heater also heats hot water to make it hotter. You'll probably notice yours kicking off an on too when it runs. When it kicks on it's not heating cold water in the tank, it's heating water that's already pretty darn hot but just dropped in temperature a few degrees. Thus, you also have a hot water heater. I sure wouldn't want one that let the water get cold every time and only kicked on when the water was cold.
(it's heating water that's already pretty darn hot but just dropped in temperature a few degrees)
Point made
RE: Miles or hours how do you plan your day's drive?
Well, how many hours do you think you have left in you? Sounds like you need to slow down and smell the roses.
LIFE IS ALL ABOUT MEMORIES AND SOMEONE TO SHARE THEM WITH
RE: Black holding tank won't drain past 2/3
Sometimes stuff gets stuck down there. Reach your arm down the hole as far as you can. When down to the max feel around for anything chunky. Grab it and squeeze it between your fingers until it gets smaller then dump some water in it (After you pull your arm out of coarse}. Do this once a month for regular maintenance. Wash your hands before cooking. I do have a self help video available. Hope this helps
I'll bet someone will read this and give it a try
I just did:S
All clear now?
RE: Black holding tank won't drain past 2/3
Sometimes stuff gets stuck down there. Reach your arm down the hole as far as you can. When down to the max feel around for anything chunky. Grab it and squeeze it between your fingers until it gets smaller then dump some water in it (After you pull your arm out of coarse}. Do this once a month for regular maintenance. Wash your hands before cooking. I do have a self help video available. Hope this helps
RE: Black holding tank won't drain past 2/3
Sometimes stuff gets stuck down there. Reach your arm down the hole as far as you can. When down to the max feel around for anything chunky. Grab it and squeeze it between your fingers until it gets smaller then dump some water in it (After you pull your arm out of coarse}. Do this once a month for regular maintenance. Wash your hands before cooking. I do have a self help video available. Hope this helps
RE: Portable air compressor
I killed two birds with one idea. I put a set of train horns on my truck that has a 5 gallon holding tank and a Viair 12 volt compressor. I ran a hard line from the tank to the back bumper with a receptacle for an air hose. Pumps up to 200 PSI in a short time. 8 years old and no issues.
2000 Dodge 2500 camper special
I have a 2000 Dodge 2500 camper special I think. I have the rear sway bar. How many rear leaf springs are on the camper special. It is a 5.9 Cummins but that should not make a difference. Thanks
RE: Biting midges or cedar gnats or no-see-ums
Calgon Morning Glory will do ya just fine for about 2 hrs per spray. Just be aware you will smell pretty. Morning Glory is the only one that works. Wal Mart
Calgon Morning Glory huh? Just as long as no one recommends extract of Hemlock we and everyone else should try it all!
As far as junipers go I'd have to respectfully disagree. These nano biters are found in areas without trees of any kind. I've read they stay within 300 feet of their birthplace and we've found them in so many places with only scrub brush. They're also called no-see-ums yet you can see um. They should be called no-feel-ums, that would be fitting. That or me-scratch-ums.
You don't know what you don't know and I am really sorry you keep getting BIT up
RE: Biting midges or cedar gnats or no-see-ums
Calgon Morning Glory will do ya just fine for about 2 hrs per spray. Just be aware you will smell pretty. Morning Glory is the only one that works. Wal Mart
