We have full-timed in a Voltage 3200 for the last year. Our total rig length is close to 40' and have found this to be a comfortable size for living, towing, and getting in and out of national, state and private campgrounds. We saw ours at a RV show ( we were looking at 5th wheels) and fell in love with the living space in the garage and the patio area. We love being able to open the back and bring the beauty of the outdoors in. We camphost and our backyard has been the pacific ocean and the rocky mountains. When we are in the rig the garage is where we eat, office, visit etc. Our kitchen/living area is rarely used. Our patio is fenced and makes a great outdoor area for our dog.
As a women I wanted a kitchen with lots of cabinets which I didn't get. I found that all those kitchen gadgets aren't necessary. I have the smaller refrigerator which is fine because even when we dry camp we are usually close to a store to re-supply. Do get the bigger microwave and the 4-season package, get rid of the blow-up bed and use that space for storage. Family and friends are nice to have visit for a few days but not much longer. Even if you have a 50 ft Class A the RV lifesyle isn't meant for long term visits.
I believe most TH have a generator on board, the fuel station is nice, bigger water, black, fresh tanks. This makes it nice to dry camp for longer periods of time. No annoying RV parks and saves money. We recently bought solar and that is really nice. We have a Tailgater for when we do watch tv.
New vs used...we might buy used next time hoping all the bugs are worked out by the first owner. On the other hand used could have a expensive hidden problem.