It is pretty flat and four lanes @ 485 miles. There are some museums in North Battleford, SK which is about 1/2 way, and a river valley. There is a Casino that allows overnight parking (free but dry camping). If you prefer hookups there are some commercial RV parks--and a Provincial Park nearby.
Diesel is usually cheaper than gas in Canada, but is still likely a "sticker shock" to folks from USA--so make sure to "fill to the gills" just before the USA border. The same is even more true for propane (4.5 gallons would be $28.00 as opposed to $10.50 in Minot). Fuel may be cheaper in Alberta than in Saskatchewan.
The prairies have a certain "stark" beauty. The highway is built where it is flat--cheaper to do it that way, but it means that the rolling hills don't get observed. The highway now bypasses most of the small towns.
There is an alternate route on Highway 17 from North Battleford which is two lane and more scenic--but a slower drive with hills.
Regina is about 200,000 people, Saskatoon about 210,000, North Battleford is a "twin city" of about 18,000. Edmonton is at 1,155,383
That's a polite way to describe it. Elk Island NP is just outside Edmonton (in prarie terms). PianoTuna will be more familair with the area but isn't the Qu'Appelle Valley between Regina and Saskatoon? I drove it once many many years ago between those cities.
Bearhawk (n): A Plansbuilt Amature Aircraft. An expensive hobby that was replaced by 2007 29FBS Jayco Jayflight G2 & 2008 F350 Crew with 6.4L Diesel
At least this adventure flew off the drawing board and running out of fuel is not as dangerous!