We travel between 70 – 74mph on the Interstate and this is equal to 2100 RPM. In a 13 hour day, we can travel 800 plus miles. At this speed we still get 10.25 mpg. In my opinion, you need to drive at what you feel comfortable.
I try to stay around 65, Just kinda got used to that speed. After hauling oversized loads up to 14' wide, 14' tall and up to 160,000 lbs. I don't need to get in a hurry.
Just came off of a 2872 mile round trip from OK through AR/LA/MS/AL/GA/FL/SC/TN/KY/and MO.
Open hiway speed limits changed from 55 to 75 depending on each state limits and hiway type. I don't have a set speed as terrain and driving conditions/heavy or lite traffic change. However if terrain and not many folks on the road I may drive 75 mph legal limits. I drive any legal speed I'm comfortabe with.
Having a construction business years back with a 1 week-2 week turn around between jobs and maybe a 600-800 mile run to the next jobsite with several trailers on the road, I found out a long tome ago which tires on my trailers worked and which didn't work as advertised.
"good judgment comes from experience, and a lot of that comes from bad judgment" ............ Will Rogers
'03 2500 QC Dodge/Cummins HO 3.73 6 speed manual Jacobs Westach
'97 Park Avanue 28' 5er 11200 gvwr two slides
I usually range from 50mph to 65mph depending on the winds and hills. When I pull a trailer I drive with respect for the road and the weather in that area.