I have driven it northbound several times in my MH and it is like any other high bridge. It is a piece of cake compared to the Mighty Mackinac Bridge in Upper Michigan. Traveled over that bridge towing our TT's for years, even walked it on Labor Day twice when they shut down the northbound lane for the Annual Labor Day walk, quite an experience.
2003 Travel Supreme MH
38KSO1 Cummins ISC 350HP
2004 Honda Pilot w/SMI Air Force One Brake Sys.
1963 Pontiac Grand Prix 20' Enclosed Car Trailer
With a little mental preparation and the usual precautions I do not think it will be a problem. Fun is travelling out of the Florida keys with an impending tropical storm with wind gusts to 40 mph across all of those bridges. Any high bridgae tends to have a cross wind which can push you around a little. Plan to cross at a less busy time and drive carefully.