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 > Your search for posts made by 'BCSnob' found 524 matches.

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  Subject Author Date Posted Forum
RE: Dog's Sleeping Quarters

Dogs will learn to sleep where you want them to sleep if you are consistent in training them to sleep in that location. Old dogs can and do learn new tricks. We have a dog bed in an unused fireplace in our house which is the preferred sleeping location for many of our dogs. Nell sleeps under the dinette in our trailer. We had a greyhound when we had our first trailer; that trailer had a jackknife couch which was the greyhound’s bed. Our second trailer didn’t have a couch and we taught the greyhound under the dinette was his bed so he was out of the way at night.
BCSnob 07/29/21 08:34pm RV Pet Stop
RE: RV Hot Skin (Exterior electrification)

I too would replace the “knob & tube” and I have replaced the first generation non metallic sheathed cable (hot & neutral) electrical wiring in my 200 year old house. It was too risky as a fire hazard. The electrician who did the work remarked that most of the wiring was still in very good condition. However, the horse hair plaster is more durable than new wallboard, the wood framing was old growth red oak which is more durable than the open grain fir used now, and the mortise and tenon joints are longer lasting than nails or screws. Newer is not always better.
BCSnob 07/27/21 12:22pm General RVing Issues
RE: Battery electric has competition

All commercial FCEVs use lithium batteries to collect and store energy from regenerative braking.
BCSnob 07/26/21 12:56pm Tow Vehicles
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

This article has a bit more information on ACE2 receptor genetic variation and comorbidities. ACE2: the molecular doorway to SARS-CoV-2
BCSnob 07/26/21 12:40pm Around the Campfire
RE: Battery electric has competition

There are home/business H2 generators but these will require electrical sources for electrolysis of water.
BCSnob 07/26/21 10:25am Tow Vehicles
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

This study found 40% of the population had antibodies and T cells that cross react with SARS-Cov-2 without prior exposure to SARS-Cov-2. The presence of preexisting SARS-CoV-2 antibody reactivity in uninfected individuals in the current study is consistent with the detection of T cell reactivity against SARS-CoV-2 in about 40% of uninfected individuals (3, 4). This raises an important question: what is the antigenic source of this antibody reactivity? Competition experiments and correlatives analyses indicate that it may, in part, be attributable to cross-reactivity against circulating coronaviruses. Most humans become infected with circulating coronaviruses by their second year of age (16). On the one hand, correlations between SARS-CoV-2 and antibody reactivity against either HKU1, N63L, or 229E, but not OC43, could reflect seasonal variations in recent exposure to common coronaviruses (10, 17). On the other hand, the high antibody reactivity to SARS-CoV in individuals in this study likely represents cross-reactivity due to the higher (>75%) sequence similarity between SARS-CoV and SARS-CoV-2 (18, 19), rather than a previous exposure to SARS-CoV. In conclusion, this study reveals common preexisting, broadly reactive SARS-CoV-2 antibodies in uninfected adults. These findings warrant larger studies to understand how these antibodies affect the severity of COVID-19, as well as the quality and longevity of responses to SARS-CoV-2 vaccines. And I wonder if these preexisting antibodies are sources of reactions to vaccination against SARS-Cov-2. Source: A majority of uninfected adults show preexisting antibody reactivity against SARS-CoV-2 If you read the linked article, the multiplex antibody assay discussed is one of my employers products.
BCSnob 07/22/21 10:40am Around the Campfire
RE: Looks like electric trucks and RVs may be delayed...

Recently published analysis of cradle to grave green house gas emissions for vehicles of various drivetrains, in several regions with their respective power production and supply chains. A GLOBAL COMPARISON OF THE LIFE-CYCLE GREENHOUSE GAS EMISSIONS OF COMBUSTION ENGINE AND ELECTRIC PASSENGER CARS July 2021 https://theicct.org/sites/default/files/Global-LCA-passenger-cars-fig1-jul2021_0.png height=300 width=500
BCSnob 07/21/21 09:17am Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

I’ve not seen a study assessing underlying causes of breakthroughs. Keep in mind vaccination yields a range of antibody titers in people; not every immune system responds to the same degree to vaccination. I did find these summaries COVID-19 Vaccine Breakthrough Infections Reported to CDC — United States, January 1–April 30, 2021 Elucidating causes of COVID-19 infection and related deaths after vaccination This summary reports a 0.01% vaccine breakthrough rate in the USA for all vaccines in use (10,262 out of 101 million persons. Of the breakthrough cases 2725(27%) were asymptomatic; 995 (10%) hospitalized; and 160 (2%) patients died.).
BCSnob 07/21/21 07:53am Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

There is also a correlation between disease severity and the amount of ace2 expressed; and the amount of ace2 expression is correlated with age (increases with age) and some comorbidities. ACE2 Expression Is Increased in the Lungs of Patients With Comorbidities Associated With Severe COVID-19 A double whammy, more ace2 receptor to bind the virus and ace2 receptor variants that will more readily bind the virus
BCSnob 07/20/21 10:11am Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

I’ve been waiting to see a study on this. In addition to sars-cov-2 genetic variants there are ace2 receptor genetic variants (223 were identified) in the human population. This preprint assess the ace2 variants and identified one that appears to limit covid-19 infection because it reduced the ability of the spike on the virus to bind to the ace2 receptor. Susceptibilities of human ACE2 genetic variants in coronavirus infection
BCSnob 07/19/21 08:34pm Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

That was not tested in the recently published phase1/2 trial of coronavac. The authors state it will be evaluated in the ongoing phase 3 trial. This study has some further limitations. First, although much evidence supports the important role of a T cell response to COVID-19,27 and such responses have been observed with use of mRNA vaccines and adenoviral-vectored vaccines,9, 10, 11, 12, 28, 29 those tests were not done in this study. However, we detected IFN-? as an indicator of T-cell responses following vaccination in our phase 1 trial among adults aged 18–59 years, and the results showed that the responses induced by CoronaVac were low.20 We will also assess the responses of type 1 and type 2 T-helper cells by CoronaVac in the ongoing phase 3 trial. The Lancet Volume 21, Issue 6, June 2021, Pages 803-812
BCSnob 07/15/21 12:47pm Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

The Novavax covid-19 vaccine (in clinical trials) is based upon a different vaccine technology than Pfizer’s mRNA vaccine (more similar to those used for the childhood vaccines). What We Know So Far About The Novavax COVID-19 Vaccine
BCSnob 07/15/21 09:02am Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

The lack of immune response from the first covid vaccine course may have been caused by residual effects of your treatments. If you had no immune response to the Pfizer vaccine and they are revaccinating you with the childhood vaccines (which were negated by your treatments) why wouldn’t they just revaccinate you for covid?
BCSnob 07/15/21 06:21am Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

One guess for the difference in attitudes (then & now) is the difference in the level of trust/belief in science
BCSnob 07/14/21 02:25pm Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

In this retrospective study of US state health department records the authors determined the prevalence of Covid-19 by age groups before the availability of vaccines and before the first report of variants in the USA. They asked the question was the percentage of covid-19 cases by age group the same as the percentage of total population for that age group. If 10-19 year olds make up 15% of the population then if there is no age correlation in susceptibility to covid-19 the 10-19 year olds should make up 15% of the covid-19 cases. What the authors found was In 16 of the 19 states experiencing surges of cases during Fall 2020, we found that (i) the prevalence of COVID-19 was significantly higher in adolescents and youth than in older adults adolescents (10-19) and youth (15-24) The 3 states that had higher rates in adults than predicted by population were: SD (during the time of the Sturgis motorcycle rally) PA & MI (during the time of multiple political rallies) MedRxiv preprint: doi: https://doi.org/10.1101/2021.07.06.21260112 It appears that younger people were more susceptible to becoming infected by covid-19 (perhaps because of behaviors). This analysis was about positive PCR tests not severity of the disease.
BCSnob 07/14/21 10:19am Around the Campfire
RE: Looks like electric trucks and RVs may be delayed...

Not the oil industry, human population growth and its increasing combustion of fossil fuels (on a per person basis). Oil is a significant component of the fossil fuels.
BCSnob 07/13/21 12:48pm Around the Campfire
RE: Looks like electric trucks and RVs may be delayed...

I have posed no contradictions; the use of pipelines is not necessarily bad. The continued (and increasing) emissions from the use of oil is bad; the impacts on the oil industry infrastructure built on the melting permafrost due to the continued emissions from the use of oil pose additional environmental threats. How would a future ruptured oil pipeline (Norilsk failed storage unit may offer hints) compare to the future environmental impact of your favorite strawman (Thatcher Pass)? So let me turn back on you what you posed to me, propose solutions. How do you propose to reduce the total emissions from the use of fossil fuels? Since you have already eliminated BEVs due to your objections to current lithium mining/extraction practices; fuel cell technology is also out (since fuel cell vehicles also use lithium batteries; regenerative braking requires batteries). Do you simply propose to do nothing?
BCSnob 07/13/21 12:02pm Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

Judging (near Ithaca, NY) went well, four 8hr days of scoring 8min runs was mentally exhausting. I received many complements on my consistency. The van radiator developed a crack on the way home; was lucky in getting it repaired on the same day. Started the ~12hr trip to the 2nd trial (near Peoria, IL); got a trailer flat within 3hrs of home (just north of Morgantown, WV) and after work hrs. Decided not to go on the remaining trip without a spare tire but decided to just come home. Spent my remaining vacation days at home training the dogs and getting farm ready for the 2 events we will be hosting later this summer and fall.
BCSnob 07/13/21 09:45am Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

Mark - didn't I read a while back that about 5% of all positive Covid tests get checked for variants? (Because it's time consuming and expensive) The Delta Variant is being found in Michigan and I see the new case rate starting to creep back up. I suspect the numbers reported are merely the tip of the iceberg.I've not seen a specific percentage of positive PCR tests that are submitted to the CDC for sequencing. The CDC does maintain a list of the number of samples sequenced and the breakdowns of the VOCs from each state and how the surveillance program works. CDC: What is Genomic Surveillance? Many states (including MI) are not listed in the CDC data tracker page for the breakdown of VOCs because the total number of samples sequenced for those states over a 4 week period was below a threshold of 300.
BCSnob 07/13/21 07:52am Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

Is there any research showing how the antibodies produced by having Covid, (presuming the UK/"Alpha" Variant) protect against the Delta variant? Or is it too early in that fight? This is from an abstract from a study recently published in Nature. Sera from convalescent patients collected up to 12 months post symptoms were 4 fold less potent against variant Delta, relative to variant Alpha (B.1.1.7). Sera from individuals having received one dose of Pfizer or AstraZeneca vaccines barely inhibited variant Delta. Administration of two doses generated a neutralizing response in 95% of individuals, with titers 3 to 5 fold lower against Delta than Alpha. Nature (2021) Reduced neutralizing titers does not mean ineffective. Another item of note is that these reported reduced titers were averages from convalescent serum samples and serum samples from vaccinated people (the number of samples was not reported in the abstract and I don't have access to this full paper) tested against the virus (delta VOC) isolated from one person (viruses can vary genomically between people and within people even within one VOC). The reduction in titers will vary between people; I suspect the variant is greater in convalescent sera (previous infection) than in sera from vaccinated people.
BCSnob 07/13/21 07:34am Around the Campfire
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