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RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365308/
et al...
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MEXICOWANDERER
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09/18/21 11:06pm |
Around the Campfire
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RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS
https://scholar.google.com.mx/scholar?q=heterologous+prime+boost+covid-19&hl=en&as_sdt=0&as_vis=1&oi=scholartPrime boosting has been analyzed by the NIH to yield 6x increase in B antigens. I am concerned about overstimulation of the immune system. i.e. a miniature cytokine event.
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MEXICOWANDERER
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09/18/21 10:40pm |
Around the Campfire
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RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS
Prime boosting has been analyzed by the NIH to yield 6x increase in B antigens. I am concerned about overstimulation of the immune system. i.e. a miniature cytokine event.
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MEXICOWANDERER
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09/18/21 07:37pm |
Around the Campfire
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RE: Group 24 Flooded to Group 31 AGM
Scam proofing
Demand a detailed list of exactly what their work will cover. Just writing "larger wire" is a scam. "Install 12 feet of 2 gauge wire from charger to batteries" is considered in detail.
A service writer can complete a detailed pro forma invoice in 5 minutes.
If they decline to do a pro forma invoice, then you have gold-plated proof you are being scammed. They can use hundreds of reasons for denial. Every last one of them is 100% B.S.
I must have completed 400 pro forma invoices in my 40 years of work. I had numbered special invoices titled PRO FORMA INVOICE
Keep in mind, the addition of a large DC to AC power inverter will demand huge cabling. But this is an add-on.
If you plan to keep your rig for at least 6 years, it may justify purchasing the sole deep cycle AGM brand on the market CONCORDE LIFELINE. You would be paying for a vastly increased number of battery cycles.
But it comes at a cost: You have to follow Concorde's maintenance instructions.
Myself, if I were in your shoes and decided to use expensive AGM batteries I would have just two chargers aboard. A Power Max 100-amp model, voltage hard set at 14.4
And a two or three amp temperature compensated battery maintenance charger.
Unless a battery is sitting at 110F permitting 14.4 volt charging for as long as five days 24 hours a day will not hurt a good quality AGM battery. So maintenance is not complicated like the recipe for baking a cake.
Charging correctly is simple. Let 14.4 volts rip until charging amperage drops to almost 0. In the case of a 100 amp hour AGM, the number is 1/2 ampere. Then switch to the maintenance charger.
Reminds me to go charge my Lifeline that has not seen a charger in almost 2 years.
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MEXICOWANDERER
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09/18/21 03:45pm |
Tech Issues
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RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS
Regarding prime + boost vaccinations would a second like mRNA booster be considered as overboosting? (A theoretical hypothesis)
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MEXICOWANDERER
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09/18/21 02:02pm |
Around the Campfire
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RE: “Pathetic quality”: RV dealers are fed up...
Was my $180,000 Crown bus conversion worth it 40 years ago? It all stayed working. It will be around for my grandchildren. To each his own.
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MEXICOWANDERER
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09/17/21 04:57pm |
General RVing Issues
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RE: Spouse left behind after death at a Campsite, what to do?
Discussion and planning are key. A death while camping means a lot of work. The spouse would be most unlikely able to break camp and drive home.
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MEXICOWANDERER
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09/17/21 04:50pm |
General RVing Issues
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RE: COVID PERSONAL EXPERIENCES
The following is a copy reposting from the professional medical COVID19 Forum
Down here the public adopted "cubrebocas" (face masks), limits on numbers of people in stores, distancing, and saturating vaccination sites with participants.
Despite the prevalence of the Delta virus, infection totals, hospitalizations, ICU cases, intubations, and fatalities are dropping daily in reporting cities and towns.
It's tough to argue against cold hard numbers.
I chat with National health care surgeons, and they all confirm the above. Masks, density limits, distance minimums, alcohol gel, and temperature verification have combined to decrease cases rather dramatically.
I went to the USA last Thursday and as far as individual measures were concerned, about 40% of people went maskless, stores were packed, and we visitors remained mindful of prevention measures.
Added Personal Note:
The infection rate just across the border in San Diego County is ramping up, while it is slumping south of the border. If your conclusion differs from mine, please don't hesitate to comment.
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MEXICOWANDERER
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09/15/21 05:44pm |
Around the Campfire
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RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS
A question with regards to inhibition of Ace 2 receptors and Rx of Ace 2 medications i.e. Enalapril / Lisinopril. A conflict?
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MEXICOWANDERER
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09/15/21 02:46pm |
Around the Campfire
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RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS
This is a report of general level of COVID Delta infection, and if what you mean is to limit this page to public professional medical announcements it is so noted. Thank you.
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MEXICOWANDERER
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09/15/21 02:42pm |
Around the Campfire
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RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS
Down here the public adopted "cubrebocas" (face masks), limits on numbers of people in stores, distancing, and saturating vaccination sites with participants.
Despite the prevalence of the Delta virus, infection totals, hospitalizations, ICU cases, intubations, and fatalities are dropping daily in reporting cities and towns.
It's tough to argue against cold hard numbers.
I chat with National health care surgeons and they all confirm the above. Masks, density limits, distance minimums, alcohol gel, and temperature verification have combined to decrease cases rather dramatically.
I went to the USA last Thursday and as far as individual measures were concerned, about 40% of people went maskless, stores were packed, and we visitors remained mindful of prevention measures.
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MEXICOWANDERER
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09/15/21 11:53am |
Around the Campfire
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RE: Remembering my best physical condition
When I was 40, I would slip into a 40 lb backpack frame then climb a thousand feet in under two miles. If you want location, GARDISKY LAKE atop Tioga Pass. Starting elevation was near ten thousand feet.
The toughest sledding was in 1983. Climbing from Muriel Lake elevation 11,300 to Goethe Lake at 12,600 ft. Over rocks and ice toting a six man inflatable raft and too much fishing gear, oars, the whole nine yards. All in the name of golden trout.
Now I need a walker just to get to the kitchen. Spinal decomposition. The memories of 41 pack trips and multiple dozens of day fishing trips is beyond price. Especially sliding down a 45° slope to a pine tree and ambushing a four pound cutthroat trout in a stream no wider than my leg is long.
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MEXICOWANDERER
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09/13/21 11:11pm |
Around the Campfire
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RE: COVID PERSONAL EXPERIENCES
I have a suspicion mRNA evolution is going to expand exponentially in controlling viral mutagens. H5N1 for example. I personally rate RNA manipulation as one of the key discoveries of the century. 50 years ago it could have been Science Fiction. Fellow alumni keep me posted about almost unbelievable advances in RNA fragment research underway in South San Francisco labs. Not themselves -- their children. We oldsters are obsolete.
I feel strongly the general public has not been made aware of the enormous contribution that researchers have made in viral control techniques. Until that magic threshold has been breached quenching probability of mutation you will remain overwhelmed I fear. But kudos for uncompensated success!
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MEXICOWANDERER
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09/08/21 05:07pm |
Around the Campfire
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RE: COVID PERSONAL EXPERIENCES
Thanks to BCSnob I now have the information needed to make a decision about a third vaccination. A second mRNA jab of Moderna atop a primer of Sinovac. There are just too many billions of unvaccinated and partially vaccinated "world-wide walking Petri Dishes" to expect no further virus mutations.
And everyone down here except for isolated indigenous, enthusiastically line up for the vaccine. There just is too little mRNA and too much Sinovac available. There are no vaccine or mask protests. Yesterday I went to Costco. My temperature was scanned at the door, member numbers were limited and mask rules are strictly enforced.
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MEXICOWANDERER
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09/08/21 03:20pm |
Around the Campfire
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RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS
Risk vs benefit ratio...
The Pfizer and Moderna medias offer an average of eight points titer gain between the two. Eighty-four percent efficacy, first jab is nothing to sneer at. Or has that study been invalidated?
The uproar over AstraZeneca was more understandable, with Oxford University finding a twenty-five point Delta T titer amplification with interval delay. But the adeno virus efficacy was forty points lower than mRNA first inoculation efficacy.
We will find out more, as mass titer studies are performed on long term inoculation intervals on the immunocompromised...the 3rd dose interval is what, now...after 90 or 120 days?
Published data regarding heterogeneous mRNA bi vaccination does not exist.
not a word about role-reversal mRNA heterogeneous efficacy. At least with the COVID-19 pathogen, and variants. Their prime boost role is to stimulate all areas of the immune system without cancelling via over stimulation. The difference in efficacy between Pfizer and Moderna seems to be keyed on the amount of vaccine given. The size of the dose.
If a university team should prime with a mRNA and follow up with an adeno or heterogeneous booster, would that make them eligible to get staked to an anthill by the NIH, the FDA or competitive corporate entities?
Having a ninety-pound weakling malfunctioning immune system makes me curious.
Once again, thank you.
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MEXICOWANDERER
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09/03/21 05:31pm |
Around the Campfire
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RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS
Question
Whereas the immunogenicity of the injected substance is the main responsible for the immune response, a secondary but not less important factor is the timing. The question asked here is what is the optimal timing for boosting in terms of higher antibody titers. Intuitively, one expects a window of optimality since a too close boost does not elicit a strong memory as it simply add, (and compete for resources) to the prime, whereas an overly delayed boost may fail to wake up the memory simply because it already faded away.
The gathered titer data is most curious. A single digit increase of titer counts is not impressive using a three to four-week interval between mRNA inoculations. Does published data exist for trials that utilized for example a twelve to fifteen-week interval?
The upcoming 3rd mRNA doses for the immunocompromised are set for a 180-day interval. How large a monitoring effort will be enacted for mass gathering of titer increase data?
Thank You!
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MEXICOWANDERER
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09/03/21 10:58am |
Around the Campfire
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RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS
https://www.nj.com/coronavirus/2021/08/moderna-vaccine-could-create-twice-as-many-covid-antibodies-as-pfizer-vaccine-study-says.html
Interesting Study
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MEXICOWANDERER
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09/01/21 04:35am |
Around the Campfire
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RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS
Here is an excerpt from Johns Hopkins regarding a CDC report
SCHOOL TRANSMISSION A case study published August 27 in the US CDC’s Morbidity and Mortality Weekly Report (MMWR) shows how quickly the highly contagious SARS-CoV-2 Delta variant can spread within a classroom of children too young to be vaccinated. The outbreak involved an unvaccinated Marin County, California (US), elementary school teacher who began showing COVID-19 symptoms on May 19, but who came to work the next 2 days, attributing the symptoms to allergies. During that time, the teacher read aloud to the class without wearing a mask, even though masks were required for staff and students while indoors. The teacher received a positive SARS-CoV-2 test on May 21 and informed the school on May 23. Several students became symptomatic on May 22, and the Marin County Department of Public Health (MCPH) initiated an investigation on May 26 to characterize the outbreak. Overall, 27 COVID-19 cases were identified, including the teacher. Among the teacher’s 24 students—all of whom were too young to be eligible for vaccination—12 of 22 who were tested received positive results between May 23-26. Notably, 8 out of 10 students who sat in the 2 front rows closest to the teacher became infected, representing an extremely high attack rate of 80%.
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MEXICOWANDERER
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08/31/21 07:30pm |
Around the Campfire
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RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS
I wish there was more data on Prime + Boost subjects.
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MEXICOWANDERER
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08/30/21 11:00am |
Around the Campfire
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RE: Storm alert Cat 4
I cannot imagine the agony of being so impoverished as to make evacuation impossible. The Big Easy is below sea level and nothing short of a 100 foot tall berm surrounding the city, gigantic rotary screw pumps and self contained power generation would limit the danger.
Down here, Las Peñas is built atop a rocky 100' to 200' tall promontory. But electric power is vulnerable and so are food stocks.
I've described how my converted bus is chain anchored and powered with a diesel generator, and has 800 gallons of exterior water reservoirs.
But I'll state this, even with massive food storage, dehumidifiers, and air conditioning, life is miserable after a hurricane. The destruction and misery of the less fortunate takes away any glow of a bloom of hyper preparation.
A gravel filled bucket is hoisted 27' atop a sea crag as an indicator. It probably could withstand 200 mph wind. It was missing this morning. A wave took it. The storm removed 70% of the tan colored sand off the beach and deposited tons of plumb size rocks.
This was a Pacific hurricane not the nightmare that came ashore in Louisiana. And to top it off they are all worried about me. Grandpa and the virus.
Please stay safe everyone.
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MEXICOWANDERER
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08/29/21 05:11pm |
Around the Campfire
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