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 > Your search for posts made by 'dturm' found 187 matches.

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RE: Protecting our pets from Covid?

Zoetis is the pharm company producing the animal COVID vaccine (this is the Pfizer spin-off company that produces animal drugs). They got an EUA license late last year and vaccinations began in "at risk" species. Almost all have been zoo residents, mostly big cats and primates. The program started at the San Diego Zoo last January. COVID vaccination for animals
dturm 09/17/21 01:54pm RV Pet Stop
RE: Why Choesterol is Biologically Important

One piece of wrong information in the video- he says the less cholesterol you take in the less the body makes. That's completely backwards - the more you take in the less the body makes and vice versa. I know some people have side effects (as with many drugs) but these are among the most prescribed drugs and studies have shown benefits in preventing heart attacks and strokes. Risk vs reward.
dturm 09/16/21 05:56pm Around the Campfire
RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS

Hypertension is a mitigating factor in COVID and the Ace2 inhibitors are used to treat hypertension. I looked this up last year as I take Lisinopril and at that time it was thought that it may actually help. There are studies going on right now. Healthsite.com
dturm 09/15/21 07:08pm Around the Campfire
RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS

Speaking of insanely good news, I've seen a couple of PR reports (take them with a grain of salt :)) that groups are working on a universal coronavirus vaccine. This would protect from all coronaviruses and their mutations - all Sars-CoV versions, cold viruses, enteric viruses. These are still experimental but show promise. UNC report Newsweek story
dturm 09/14/21 02:15pm Around the Campfire
RE: A very old stray {The Old Fella Story}

Sorry to hear this Dale. That's a long trip solo, take care.
dturm 09/07/21 08:21am RV Pet Stop
RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS

This is the question that is determined during initial trials. Initial dose and timing intervals are guessed based on previous vaccines, results in animal trials then tested in people. Pfizer and Moderna chose different intervals and dosage volumes for their human trials. The results of the trials and the serious nature of the pandemic made immediate approval appropriate. They are still doing trials with different doses (about 1/3 the dose for children under 12) and different lengths between boosters. I would assume that they will accumulate additional data and seek licensing based on these data.
dturm 09/03/21 11:20am Around the Campfire
RE: A very old stray {The Old Fella Story}

I'm not surprised by the Moderna producing more antibodies as their shot had 100 micrograms dose while the Pfizer had 30 microgram. This is probably why they are going to recommend a 3rd shot the end of this month. Stay safe on your travels, and have fun.
dturm 09/01/21 12:57pm RV Pet Stop
RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS

Steve that's great. My wife had her third Pfizer 10 days ago. No plans for antibody testing at this point.
dturm 09/01/21 09:19am Around the Campfire
RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS

Effective? There are protocols that are way more effective than early last year. I know many drugs and combinations are used along with supportive care depending on severity of the cases. The development of monoclonal antibodies given early in the course of the disease is reported to be helpful. Bottom line, there is no one treatment that guarantees a good outcome. As a rule in medicine, prevention is the best medicine.
dturm 08/31/21 05:51pm Around the Campfire
RE: A very old stray {The Old Fella Story}

Just read a preprint of a study out of Israel. Good news is that they found a 3rd booster provided big improvement in protection from Delta, many fewer infections in vaccinated individuals. They started giving 3rd boosters to people >60 in July. They postulate that this will aid greatly is stopping the Delta spread. Sandy got her 3rd Pfizer vx about 10 days ago (per her rheumatologist's recommendation). We too are masking and avoiding large gatherings.
dturm 08/30/21 01:58pm RV Pet Stop
RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS

Politico report on recent cohort study CDC report Vaccinated still 80% protection from infection with vaccine.
dturm 08/30/21 10:37am Around the Campfire
RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS

Jim, I understand your frustration but there are two major reasons why vaccination is still a good idea. 1. As Mark listed above, unvaccinated people are 17X more likely to end up in the hospital. In all probability the cases you and your family members had would have been more serious. 2. Many people vaccinated do not get re-infected. The more we can limit the number of times this virus reproduces through infection, the greater the chance we can limit mutations that cause problems, like the Delta variant. Your experiences are evidence why it's still important to take reasonable preventive measures.
dturm 08/30/21 09:44am Around the Campfire
RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS

Definition of Vaccine from Wikipedia https://en.wikipedia.org/wiki/Vaccine A vaccine is a biological preparation that provides active acquired immunity to a particular infectious disease. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or killed forms of the microbe, its toxins, or one of its surface proteins. The agent stimulates the body's immune system to recognize the agent as a threat, destroy it, and to further recognize and destroy any of the microorganisms associated with that agent that it may encounter in the future. Vaccines can be prophylactic (to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen), or therapeutic (to fight a disease that has already occurred, such as cancer). Some vaccines offer full sterlizing immunity, in which infection is prevented completely.
dturm 08/29/21 05:08am Around the Campfire
RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS

Ivermectin has been in the news recently and real accurate information about this drug should be shared. Most people who follow this thread probably are not considering Ivermectin as a treatment but probably do have friends or family members who are. As a veterinarian, I have prescribed and used this drug more than any other since the mid 80s. Below is a information from the NIH and CDC. NIH CDC The most important take away is: Ivermectin has been shown to inhibit the replication of SARS-CoV-2 in cell cultures. However, pharmacokinetic and pharmacodynamic studies suggest that achieving the plasma concentrations necessary for the antiviral efficacy detected in vitro would require administration of doses up to 100-fold higher than those approved for use in humans. In the real world, we primarily use Ivermectin in my branch of veterinary medicine as a heartworm preventive dosed at 6-12 mcg /kg (that’s micrograms NOT milligrams) once a month. At this dosage level this drug is extremely safe for dogs and yet there are some (very, very few) minor reactions. It is also used at 10X (or more) dose more frequent dosage (daily) for some ectoparasite problems (mange). This drug becomes problematic for many individuals at this level and is contraindicated for those specifically with a ABCB1 (formerly MDR1) mutation found frequently in collie related breeds. THIS MUTATION IS ALSO FOUND IN PEOPLE. The most common serious reactions have to do with neurological issues leading to seizures in susceptible individuals. Similar adverse reactions have been reported in all species we treat, horses, cattle, sheep, rodents and birds, reptiles and probably others I’m not aware of. The major compounding issue using animal drugs is the dosage calculations. One has to convert the dose micrograms per kg to pounds, to milligrams, to the animal strength (1% in the cattle version) to the milliliter liquid dose. I do this calculation frequently and always double check and have someone check my work. People not familiar with these values and the math are prone to making mistakes, and with the concentrations of these medications MISTAKES ARE SERIOUS. Also of interest is the interaction of concurrent use of other medications with Ivermectin, specifically statins, warfarin, calcium channel blockers. Do a search about calls to poison control centers about ivermectin and you will get multiple hits from many states with recent astronomical increases in calls. Contrary to “news” talking heads and internet sites, this drug is not innocuous. It should only be used under the supervision of YOUR doctor that knows your history and concurrent medication history, and frankly until there is conclusive evidence that it actually safely works to prevent or treat COVID, there are better, safer and approved treatment and preventives. Doug DVM
dturm 08/28/21 07:23am Around the Campfire
RE: A very old stray {The Old Fella Story}

Glad that your wife is doing better. I know it seems like many people who got vaccinated are getting COVID and are reported in the press. The reporting skews things as we don't see the vaccinated people who were also exposed and NOT infected. The only way we get this information is through cohort studies. This is where all people (both vaccinated and unvaccinated) in a population are routinely tested. Stats can be developed to compare relative infection rates and protective effects of the vaccine. These are being done and stats still show amazing protection from the vaccines. Certainly not as effective with Delta as with the original wild strain and also with waning immunity as time from vaccination lengthen. The bottom line is that as long as this thing is being spread like it is now, we're all at risk. The only way to tamp this thing down is to vaccinate more people and continue to take public health measures to mitigate spread.
dturm 08/27/21 07:18pm RV Pet Stop
RE: A very old stray {The Old Fella Story}

Sorry to hear about your COVID adventures. Florida is a high community spread area right now. Were you guys vaccinated? Also, consider inquiring about monoclonal antibody treatment. Given early it can make a difference in severity and eventual outcome. Also, I think the monoclonal antibody treatment is free - treatment costs are picked up by one of the congressional acts.
dturm 08/27/21 12:27pm RV Pet Stop
RE: Goodbye old friend, You will be missed

Sorry for your loss. It seems you had many good years and experiences with her and you eased her final years and repaid some of the companionship and love she gave during her life.
dturm 08/27/21 04:56am RV Pet Stop
RE: Views on when to/not to allow a dog to be social

We never allow them to interact with other dogs. Although there is unlikely to be a problem, it is so unpredictable as to the aggressiveness of the other unknown animals or any health issues we just don’t take the chance. My position too. I've seen the results of meet and greets and dog parks too many times to risk taking a chance. Socialization can occur with other than random animals, your own dogs and neighbors where you know behavior and health status. Also, until your dog has completed his puppy series of shots, it's not a good idea to mix. Their version of social distancing.
dturm 08/26/21 12:56pm RV Pet Stop
RE: COVID PERSONAL EXPERIENCES

My other half has RA and is on immunosuppressants. She got her 3rd Pfizer vaccination yesterday (as recommended by her rheumatologist) and so far nothing other than a little sore arm.
dturm 08/21/21 07:36am Around the Campfire
RE: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS

I see reports that they are still using the monoclonal antibodies as treatment, but I have not heard anyone speculate on the efficacy in Delta infections. The difficulty in determining breakthrough case incidence is that a huge majority are "probably" not reported, minor cases in vaccinated people where testing isn't even done. The stats compiled are from "cohort" studies where a population is regularly tested (both vaccinated and not) and positives are reported.
dturm 08/18/21 03:19pm Around the Campfire
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