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Open Roads Forum  >  Around the Campfire  >  General Topics

 > 2019–2022 CORONAVIRUS PANDEMIC POSTINGS

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BCSnob

Middletown, MD

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Posted: 08/30/21 11:16am Link  |  Quote  |  Print  |  Notify Moderator

way2roll wrote:

the loss of efficacy after months and further lack of efficacy with the delta.

The vaccines are less effective against Delta not ineffective.

BNT162b2 and mRNA-1273 COVID-19 vaccine ........t the Delta (B.1.617.2) variant in Qatar

Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant

CDC

Effectiveness of COVID-19 vaccines again........t variants of concern in Ontario, Canada


I can provide more studies

BCSnob

Middletown, MD

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Posted: 08/30/21 11:18am Link  |  Quote  |  Print  |  Notify Moderator

There is a difference between individual results and population based results.

We don’t have a proven method to assess an individual’s protection against infection; each person’s immune system is different. Did you notice there are risk factors correlated to breakthrough infections?

BCSnob

Middletown, MD

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Posted: 08/31/21 02:25pm Link  |  Quote  |  Print  |  Notify Moderator

Correlation between times to SARS-CoV-2 symptom onset and secondary transmission undermines epidemic control efforts
medRxiv Preprint 31Aug2021
Authors have estimated the time to transmission of SARS-CoV-2 from the infector to the infectee ("generation interval") and the time to onset of symptoms in the infector ("incubation period") from data in Japan.

Quote:

For the dataset of 257 pairs with symptomatic infectors, most infectors (50.2%) and infectees (44.4%) were between 30–59 years of age. There were fewer female infectors (30.7%) detected compared to female infectees (51.0%). Age and sex distributions of infectors and infectees are shown in Extended Data Fig. 2.

Quote:

We found that 63.2% of pairs experienced presymptomatic transmission, defined as the generation interval being shorter than the incubation period

Quote:

Most identified transmission pairs had contact in the household or in settings related to social behavior, such as eating at restaurants, visiting nightlife, singing karaoke, attending sports events, listening to live music, visiting gyms, or meeting with friends, relatives, acquaintances, etc. (Table 1).


This study was for an earlier variant. The authors addressed possible differences between the variants
Quote:

As SARS-CoV-2 variants begin to dominate transmission in many countries,48–50 it remains to be seen whether the mean and variance of the generation interval and incubation period for the new variants of concern (VOC) will be similar to estimates presented in this, or previous studies. It has been suggested that the Alpha (Pango lineage B.1.1.7) variant could have longer generation intervals,51 and may therefore be more responsive to interventions targeted towards speed, such as contact tracing.52 However, a study using Singapore transmission pairs did not find a large difference (>1 day) between the serial interval of wild-type and Delta (Pango lineage B.1.617.2) variant SARS-CoV-2 infections.53 As the mean serial interval can approximate the mean generation interval, this finding may indicate that the generation interval of the Delta variant will not vary much from that of wild-type SARS-CoV-2. Similarly, a preprint analysis of Delta variant cases from China estimated an incubation period of 5.8 days,54 which resembles the results from a meta-analysis on wild-type SARS-CoV-2 incubation periods.29

The author's main point was that since contact tracing won't occur until after the infector has developed symptoms; contact tracing and screening for symptoms (temperature checks) will not be very effective at controlling the spread of the infection.

pianotuna

Regina, SK, Canada

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Posted: 08/31/21 05:26pm Link  |  Quote  |  Print  |  Notify Moderator

Is there any effective treatment for unvaccinated folks who contract covid?


Regards, Don
My ride is a 28 foot Class C, 256 watts solar, soon to have SiO2 batteries, 3000 watt Magnum hybrid inverter, Sola Basic Autoformer, Microair Easy Start.

dturm

Lake County, IN

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Posted: 08/31/21 05:51pm Link  |  Quote  |  Print  |  Notify Moderator

Effective? There are protocols that are way more effective than early last year. I know many drugs and combinations are used along with supportive care depending on severity of the cases. The development of monoclonal antibodies given early in the course of the disease is reported to be helpful.

Bottom line, there is no one treatment that guarantees a good outcome.

As a rule in medicine, prevention is the best medicine.


Doug & Sandy
Kaylee (12 year old Terrier of some sort), Sasha 3 yr old Golden
Kaiya at the Rainbow Bridge
2008 Southwind
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Check out blog.rv.net


Moderator

Tennessee

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Posted: 08/31/21 05:56pm Link  |  Quote  |  Print  |  Notify Moderator

Quote:

Is there any effective treatment for unvaccinated folks who contract covid?


Well, treatment most likely will be in a hospital: Unvaccinated

pianotuna

Regina, SK, Canada

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Posted: 08/31/21 07:00pm Link  |  Quote  |  Print  |  Notify Moderator

The person in question is 10 years old. So that is why no vaccination was done.

BCSnob

Middletown, MD

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Posted: 08/31/21 07:18pm Link  |  Quote  |  Print  |  Notify Moderator

The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies
Cell Volume 184, Issue 15, 22 July 2021, Pages 3949-3961

MEXICOWANDERER

las peñas, michoacan, mexico

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Posted: 08/31/21 07:30pm Link  |  Quote  |  Print  |  Notify Moderator

Here is an excerpt from Johns Hopkins regarding a CDC report

SCHOOL TRANSMISSION A case study published August 27 in the US CDC’s Morbidity and Mortality Weekly Report (MMWR) shows how quickly the highly contagious SARS-CoV-2 Delta variant can spread within a classroom of children too young to be vaccinated. The outbreak involved an unvaccinated Marin County, California (US), elementary school teacher who began showing COVID-19 symptoms on May 19, but who came to work the next 2 days, attributing the symptoms to allergies. During that time, the teacher read aloud to the class without wearing a mask, even though masks were required for staff and students while indoors. The teacher received a positive SARS-CoV-2 test on May 21 and informed the school on May 23. Several students became symptomatic on May 22, and the Marin County Department of Public Health (MCPH) initiated an investigation on May 26 to characterize the outbreak. Overall, 27 COVID-19 cases were identified, including the teacher. Among the teacher’s 24 students—all of whom were too young to be eligible for vaccination—12 of 22 who were tested received positive results between May 23-26. Notably, 8 out of 10 students who sat in the 2 front rows closest to the teacher became infected, representing an extremely high attack rate of 80%.

MEXICOWANDERER

las peñas, michoacan, mexico

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Online
Posted: 09/01/21 04:35am Link  |  Quote  |  Print  |  Notify Moderator

https://www.nj.com/coronavirus/2021/08/m........bodies-as-pfizer-vaccine-study-says.html

Interesting Study

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