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Open Roads Forum  >  Around the Campfire  >  General Topics

 > 2019–20 CORONAVIRUS PANDEMIC POSTINGS

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BCSnob

Middletown, MD

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Posted: 09/22/20 10:33am Link  |  Quote  |  Print  |  Notify Moderator

Here is another study showing there has been no difference in viral loads between three age groups: less than 5 years, 5-17 years, and older than 17 years. The study examined data from 5,544 positive covid tests in patients from CA tested in two different labs.
Quote:

Laboratory A serves the UC San Francisco health care system, as well as local clinics and also 42 provides tests to the county health departments in 26 California counties. Laboratory B serves 43 principally the UC Davis health care system and partner clinics/hospitals centered in Sacramento, CA.
The viral loads were determined in all the samples. and no significant difference in load was found between these age groups. The youngest did not have a higher viral load than the other age groups.

Source:
Nasopharyngeal SARS-CoV2 viral loads in young children do not differ significantly from those in older children and adults
doi: https://doi.org/10.1101/2020.09.17.20192245

BCSnob

Middletown, MD

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Posted: 09/22/20 10:45am Link  |  Quote  |  Print  |  Notify Moderator

Turtle n Peeps wrote:

No really good way to tell why Fauci flip flopped on the mask issue either?
Sure there is; over months science increased our understanding of how this virus spreads and then there were updates to recommended mask use. I'm sorry if this information is raining on your storyline; have some more cool-aid and you'll feel better.

BCSnob

Middletown, MD

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Posted: 09/22/20 11:10am Link  |  Quote  |  Print  |  Notify Moderator

This article indicates surgical masks protect against the spread covid in aerosols.

Respiratory virus shedding in exhaled breath and efficacy of face masks
Nature Medicine volume 26, pages676–680(2020)

Quote:

Abstract
We identified seasonal human coronaviruses, influenza viruses and rhinoviruses in exhaled breath and coughs of children and adults with acute respiratory illness. Surgical face masks significantly reduced detection of influenza virus RNA in respiratory droplets and coronavirus RNA in aerosols, with a trend toward reduced detection of coronavirus RNA in respiratory droplets. Our results indicate that surgical face masks could prevent transmission of human coronaviruses and influenza viruses from symptomatic individuals.


This pre-print posted today has a good discussion on the effectiveness of face masks in decreasing the spread of covid (be it by filtering exhaled virus or filtering inhaled virus. The studies on the effectiveness of facemasks were for covid, be it transmitted by droplets or in aerosols.

Quote:

Many studies have reported that facial masks substantially reduce the infection risk, which applies to disposable surgical masks as well as reusable cloth masks (Chu et al., 2020; Esposito et al., 2020; Fischer et al., 2020; Howard et al., 2020; Leung et al., 2020; MacIntyre and Chughtai, 2020). Mueller et al. (2020) found that, when worn as designed, surgical and cloth masks have filtration efficiencies of 53–75% and 28–90%, respectively. Mask wearing works in two ways, by preventing infected subjects from spreading droplets and aerosols, and by limiting exposure through inhalation. Verma et al. (2020) report that homemade masks with multiple fabric layers effectively reduce droplet dispersal. Drewnick et al. (2020) investigated many materials, and measured a large range of filtration efficiencies, from about 10% to 100%. Materials with small leak areas, e.g. 1–2%, were shown to have substantially reduced efficiency. By the stacking of a number of fabric layers, homemade masks appeared to achieve good filtration efficiencies of about 50 80% for 0.5–10 ?m particles, and 30–60% for 30–250 nm particles. These results agree with Shakya et al. (2017), and confirm that surgical masks are generally more efficient than homemade cloth products (Davies et al., 2013).

The filtering efficiency of medical and non-medical masks is typically exceeded by N95 (filter 95% of the particles), FFP2 (filter ?94%) and FFP3 (?99%) respirators, which are recommended for health-care workers (Chu et al. 2020; Howard et at., 2020). The universal, public wearing of masks (not respirators) by at least 80% of the population was shown to be particularly effective in reducing the spreading of COVID-19 (De Kai et al., 2020). The effectiveness of using face masks by the general population obviously increases with their filter efficiency, but even if it is low, the benefits are apparent (Worby and Chang, 2020). By studying policies in different countries, De Kai et al. (2020) found a strong correlation between mask wearing and both daily and peak growth reduction of COVID-19, with successful application in countries such as China, South Korea and Japan, where this practice is ubiquitous.



Surgical masks are relatively efficient in this respect, but also home-made cloth masks can contribute, albeit with lower efficiency (Fischer et al., 2020). Drewnick et al. (2020) reported that avoiding leaks in masks is particularly important to have good overall efficacy. When masks with a sufficient number of layers of good material (especially fluffy textiles) and with proper fit are used, there could be substantial inhalation protection. The masks reduce SARS-CoV-2 emissions in both droplets and aerosol particles. At emission, the particles are initially wet (small droplets), likely remaining so under the mask.



Source:
Aerosol transmission of COVID-19 and infection risk in indoor environments
doi: https://doi.org/10.1101/2020.09.22.20199489


* This post was last edited 09/22/20 12:44pm by BCSnob *   View edit history

MEXICOWANDERER

las peñas, michoacan, mexico

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Posted: 09/22/20 01:20pm Link  |  Quote  |  Print  |  Notify Moderator

There is an overabundance of factual evidence that masks and distancing works. Weddings with 100 atendees sans masks and distancing of which 20+ developed COVID within a couple of weeks. A cantina in the state of Oaxaca, which had 30 regular customers. No mask, no distancing, and little ventilation. Twenty four of the thirty developed Covid19, and four died including the bartender.

I am sitting in a house, solo. In "cuarantina". A 75 degree breeze is flapping drapes and rattling venetian blinds. I shop fewer than weekly. Hoping my exposure amounts to less than critical dosage. No shopping at stores that do not satisfy my criteria for safe distancing (Like the absurdly packed checkout at Home Depot). COSTCO here has multiple celing fans in the checkout area and will forcefully eject "customers" who refuse to abide by the mask and social distancing guidelines. In the checkout area clearly marked distancing spacing exists on the concrete floor. One departure means one admitted density control. Temperature taking mandatory for admittance. And finally, the cops come and haul violators away. They go to the police station and pay a fine of forty six dollars and there is no monkey business with bribery.

Isn't it amazing how much higher the rate of infection is for cities in Mexico that have subways that get packed during rush hour? And dismissal of concern by people age 30 or younger?

I have two housekeepers, who alternate three days duty weekly. They understand clearly that they will receive full pay if they or anyone in their family shows signs of infection. I wish I knew post infection data that would show clear guidance of how long transmission danger exists after the symptoms of infection go away. When they work in one room I am in another. With a breeze in the house. I have aerosol Lysol and Clorox and they apply a cup of bleach to the toilet and wipe it down after use.

I just turned 74. I intend to reach 75 so I can maintain a financial lifeline to my daughter and grand kids.

MEXICOWANDERER

las peñas, michoacan, mexico

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Posted: 09/22/20 01:28pm Link  |  Quote  |  Print  |  Notify Moderator

And a separate and distinct Thank you to the professionals like BCSnob who donate time and effort to maintain focus and accuracy about COVID19.

LJAZ

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Posted: 09/23/20 09:56am Link  |  Quote  |  Print  |  Notify Moderator

The initial recommendations that masks were unnecessary were due to the thought that Covid transmission was similar to the seasonal flu where people already know they're sick by the time they can transmit the disease. Therefore a mask didn't do much because the person would be home in bed and not out in public spreading it. Later it was determined that a Covid infected person is capable of spreading the disease for up to 2 weeks before the onset of symptoms, and in some cases remained asymptomatic. So instead of being home in bed, infected people were out and about spreading the disease without knowing they were sick. This is where the mask becomes effective in reducing the spread and led to the change in recommendations.


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Posted: 09/23/20 11:00am Link  |  Quote  |  Print  |  Notify Moderator

Please keep the discussion on the science and not the politics of Covid.

MEXICOWANDERER

las peñas, michoacan, mexico

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Posted: 09/23/20 12:39pm Link  |  Quote  |  Print  |  Notify Moderator

MISTER MODERATOR your request is becoming increasingly difficult. [emoticon]
There was an is no reason given for the rest of the world resuming testing of a Covid19 Phase III TEST while the USA BALKS for no given reason. The adverse reaction happened in Great Britain and they have long since resumed trials. Maybe our illucidated medical advisors can shed some light on this.



-----------------
We understand the difficulty, we do. Politics have never cured anyone; science has. Keep in mind we, as moderators, have to continually bite our tongues on this issue as well as many others; we don't always succeed but we sure try. [emoticon] (Mod)

* This post was edited 09/23/20 04:14pm by an administrator/moderator *

BCSnob

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Posted: 09/23/20 01:00pm Link  |  Quote  |  Print  |  Notify Moderator

If the AstraZeneca phase 3 vaccine trial in the USA was put on hold, why does the NIH page for this trial list:

Quote:

Recruitment Status : Not yet recruiting
First Posted : August 18, 2020
Last Update Posted : August 18, 2020


ClinicalTrials.gov Identifier: NCT04516746

pianotuna

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Posted: 09/23/20 05:30pm Link  |  Quote  |  Print  |  Notify Moderator

Hi BCSnob,

I think this may be why it is still paused in USA. "“No final diagnosis”

AstraZeneca responded with a statement saying: “There is no final diagnosis and there will not be one until more tests are carried out.” However, NIH director Francis S. Collins, MD, PhD, seemed to give credence to the Times’ report when he told a Senate committee last week that the reason for the trial pause was a “spinal cord problem.”"

https://www.genengnews.com/news/astrazen........er-biontech-eye-14000-more-participants/


Regards, Don
My ride is a 28 foot Class C, 256 watts solar, soon to have SiO2 batteries, 3000 watt Magnum hybrid inverter, Sola Basic Autoformer, Microair Easy Start.

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